SYNTHESIS AND CYCLIZATION OF N-(4-PHENOXYPHENYL)-β-ALANINES

Authors

  • V. Mickevicius Kaunas University of Technology, Kaunas 50299
  • M. Mickevicius Kaunas University of Technology, Kaunas 50299
  • R. Vaickelioniene Kaunas University of Technology, Kaunas 50299

Keywords:

arylidene hydrazides, dihydropyrimidinediones, N-substituted β-alanines, 4-carboxy-2-pyrrolidinones

Abstract

We have used the reaction of 4-aminodiphenyl ester with acrylic, methacrylic, crotonic, and itaconic acids to synthesize N-substituted β-alanines, which undergo ring closure to form derivatives of dihydropyrimidinedione and 4-carboxy-2-pyrrolidinone. We have studied the reactions of acylation and recyclization of the dihydropyrimidinedione ring, and we have synthesized derivatives of 4-carboxy-1-(4-phenoxyphenyl)-2-pyrrolidinone: arylidene hydrazides, 2[(2-oxo-4-pyrrolidinyl-1-(4-phenoxy-phenyl)]benzimidazole.

How to Cite
Mickevicius, V.; Mickevicius, M.; Vaickelioniene, R. Chem. Heterocycl. Compd. 2004, 40, 781. [Khim. Geterotsikl. Soedin. 2004, 911.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000040775.12740.81

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Published

2004-06-25

Issue

No. 6 (2004)

Section

Original Papers