A NEW ROUTE TO PARTIALLY HYDROGENATED THIAZOLO[3,2-<i>a</i>]PYRIDINE

Authors

  • А. Д. Дяченко Taras Shevchenko National Pedagogical University, Lugansk 91011
  • С. М. Десенко V. N. Karazin National University, Kharkov 61070
  • В. Д. Дяченко Taras Shevchenko National Pedagogical University, Lugansk 91011
  • А. Н. Чернега Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

Keywords:

2-bromocyclohexanone, ammonium pyridin-2-thiolates, thiazolo[3,2-a]pyridines, alkylation, dehydration, dehydrogenation, X-ray crystallography, cyclization

Abstract

Partially hydrogenated thiazolo[3,2-a]pyridines have been synthesized by the interaction of functionally substituted ammonium di- and tetrahydropyridine-2-thiolates with bromocyclohexanone. The structure of 6,8-dicyano-3-hydroxy-5-oxo-1,3-tetramethylene-2,3,4,5,6,7-hexahydrospiro[thiazolo-
[3,2-a]pyridine-7,1'-(4'-methylcyclohexane)] has been determined by X-ray crystallography.

How to Cite
Dyachenko, A. D.; Desenko, S. M.; Dyachenko, V. D.; Chernega, A. N. Chem. Heterocycl. Compd. 2004, 40, 650. [Khim. Geterotsikl. Soedin. 2004, 765.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000037322.78539.cc

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Published

2004-05-25

Issue

No. 5 (2004)

Section

Original Papers