INTERACTION OF 5-ARYL-2,3-DIHYDROFURAN-2,3-DIONES WITH FUNCTIONALLY SUBSTITUTED HYDRAZIDES AND DIAMINOGLYOXAL DIPHENYLHYDRAZONE

Authors

  • Д. Д. Некрасов Institute of Technical Chemistry, Urals Branch of the Russian Academy of Sciences, Perm
  • С. В. Кольцова Institute of Technical Chemistry, Urals Branch of the Russian Academy of Sciences, Perm
  • М. А. Радишевская Perm D. N. Pryanishnikov Agricultural Academy, Perm 614990

Keywords:

5-aryl-2,3-dihydrofuran-2,3-diones, aroylpyruvoylhydrazides, 5,6-bis(phenylhydrazono)-3-aroylmethylenepiperazin-2-ones, biological activity, decyclization, recyclization

Abstract

The reaction of 5-aryl-2,3-dihydrofuran-2,3-diones with cyanoacetylhydrazide, o-(hydrazino-carbonyl)phenylthiourea, and the diphenylhydrazone of diaminoglyoxal leads to the synthesis of the corresponding N-cyanoacetylhydrazides of aroylpyruvic acids, 2-(N-aroylpyruvoylhydrazinocarbonyl)-phenylthioureas, and 5,6-bis(phenylhydrazono)-3-aroylmethylenepiperazin-2-ones. The results of the primary investigation of the biological activity of N-cyanoacetylhydrazides of aroylpyruvic acids are given.

How to Cite
Nekrasov, D. D.; Kol'tsova, S. V.; Radishevskaya, M. A. Chem. Heterocycl. Compd. 2004, 40, 301. [Khim. Geterotsikl. Soedin. 2004, 374.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000028625.78327.63

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Published

2004-03-25

Issue

No. 3 (2004)

Section

Original Papers