SYNTHESIS AND PROPERTIES OF ETHYL ESTERS OF 4-DIALKYLAMINO-2-METHYLTHIOTHIENO[2,3-<i>d</i>]-PYRIMIDINE-6-CARBOXYLIC ACIDS

Abstract

The reaction of 4-dialkylamino-6-chloro-2-methylthiopyrimidine-5-carbaldehydes with ethyl mercaptoacetate in the presence of triethylamine gives the corresponding ethyl esters of thieno[2,3-d]-pyrimidine-6-carboxylic acids. These esters were subjected to alkaline hydrolysis, hydrazinolysis, and lithium aluminum hydride reduction to give the corresponding acids, hydrazides, and (thieno[2,3-d]-pyrimidin-6-yl)methanols.

How to Cite
Tumkevicius, S.; Kaminskas, A. Chem. Heterocycl. Compd. 2003, 39, 6641. [Khim. Geterotsikl. Soedin. 2003, 765.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1025114703659