PYRIMIDO[4,5-<i>f</i>]QUINAZOLINES

Authors

  • Н. Н. Тонких Riga Technical University, Riga LV-1048
  • А. Я. Страков Riga Technical University, Riga LV-1048
  • М. В. Петрова Riga Technical University, Riga LV-1048

Keywords:

6-(dimethylamino)methylen-5-oxo-5,6,7,8-tetrahydroquinazolines, 2,8-disubstituted 5,6-dihydro[4,5-f]quinazolines

Abstract

The corresponding 6-dimethylaminomethylen-5-oxo-5,6,7,8-tetrahydroquinazolines were obtained from reactions of 2-substituted and 2,7-disubstituted 5-oxo-5,6,7,8-tetrahydroquinazolines with the dimethylacetal of DMF. Sixteen 2,8-disubstituted 5,6-dihydropyrimido[4,5-f]quinazolines were obtained from the reaction of 2-phenyl- and 6-(dimethylamino)methylen-5-oxo-2-(4-pyridyl)-5,6,7,8-tetrahydroquinazolines with guanidine and eight amidines. The corresponding 6-hydroxymethylene derivative was obtained by hydrolysis of 6-(dimethylamino)methylen-5-oxo-1-phenyl-5,6,7,8-tetrahydroquinazoline.

How to Cite
Tonkikh, N. N.; Strakovs, A.; Petrova, M. V. Chem. Heterocycl. Compd. 2003, 39, 520. [Khim. Geterotsikl. Soedin. 2003, 603.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1024725716147

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Published

2003-04-25

Issue

No. 4 (2003)

Section

Original Papers