STUDIES WITH POLYFUNCTIONALLY SUBSTITUTED HETEROCYCLES: SYNTHESES OF POLYFUNCTIONALLY SUBSTITUTED ISOQUINOLINES

Authors

  • Yehya M. Elkholy Department of chemistry, Faculty of Science, Helwan University, AinHewan, Cairo

Keywords:

electrophilic reagents, isoquinoline, pyridinethiones, thieno[3,4-c]pyridine

Abstract

Three-component reaction of acetaldehyde, cyanothioacetamide and malononitrile results in 6-amino-3,5-dicyano-4-methylpyridine-2(1H)-thione. The latter reacts with different chemical reagents to afford new substituted isoquinolines and their fused derivatives which show high fungicidal and bactericidal activities.

How to Cite
Elkholy, Y. M. Chem. Heterocycl. Compd. 2002, 38, 1342. [Khim. Geterotsikl. Soedin. 2002, 1525.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1022126409122

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Published

2002-11-25

Issue

No. 11 (2002)

Section

Original Papers