SYNTHESIS AND BIOLOGICAL PROPERTIES OF ISOQUINOLINES SPIROFUSED WITH CARBOCYCLES AND HETEROCYCLES AT POSITION 4

Authors

  • В. М. Кисель Taras Shevchenko Kiev National University, Kiev
  • Е. О. Костырко Taras Shevchenko Kiev National University, Kiev
  • В. А. Ковтуненко Taras Shevchenko Kiev National University, Kiev

Keywords:

biologically active substances, heterocyclic spiranes, spirofused isoquinolines

Abstract

Published data on the synthesis and biological properties of isoquinolines spirofused with carbocycles and heterocycles at position 4 are reviewed. The methods of synthesis are classified according to the formation of the isoquinoline fragment or the carbocycle or heterocycle fused with it during the construction of the spirocyclic system. Data on the biological activity are arranged according to the types of action exhibited by the compounds.

How to Cite
Kisel, V. M.; Kostyrko, E. O.; Kovtunenko, V. A. Chem. Heterocycl. Compd. 2002, 38, 1295. [Khim. Geterotsikl. Soedin. 2002, 1475.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1022166023234

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Published

2002-11-25

Issue

No. 11 (2002)

Section

Review Articles