ALKYL ESTERS OF 2-[5-CHLORO(BROMO)-6-METHOXY-4-METHYLPYRIMIDINYL-2-OXY]ALKANOIC ACIDS
Keywords:
halosuccinimides, pyrimidinyloxyalkanoic acid nitriles and esters, cyanomethylating mixtureAbstract
The reaction of a mixture of formaldehyde and sodium cyanide or of lactic acid nitrile with trimethyl(6-methoxy-4-methylpyrimidinyl-2)ammonium chloride give the 2-(6-methoxy-4-methylpyrimidinyl-2-oxy)alkanoic acid nitriles. They were subsequently converted to the corresponding alkyl esters by a Pinner reaction and then to their 2-(5-halo-6-methoxy-4-methylpyrimidinyl-2-oxy) derivatives using N-halosuccinimides.
How to Cite
Dovlatyan, V. V.; Eliazyan, K. A.; Pivazyan, V. A.; Kazaryan, E. A.; Engoyan, A. P. Chem. Heterocycl. Compd. 2002, 38, 1081. [Khim. Geterotsikl. Soedin. 2002, 1237.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1021205315228