BASIC AND ACIDIC CHARACTERISTICS OF COMPOUNDS OF THE 3-AMINO-1-IMINO-1H-ISOINDOLE SERIES
Keywords:
N,N'-diaryl- and N,N'-dimethyl-substituted 3-amino-1-imino-1H-isoindoles, deprotonation, methylation, protonation, spectral characteristicsAbstract
The basic and acidic characteristics of N,N'-diaryl- and N,N'-dimethyl-substituted 3-amino-1-imino-1H-isoindoles, which are determined by electronic factors related to the nature of the substituents at the exocyclic nitrogen atoms, were studied. Electron-donating alkyl groups lead to an increase in the basicity of these compounds. The introduction of aryl groups containing electron-withdrawing substituents (NO2, COMe) at the p-positions leads to significant weakening of the basic characteristics and strengthening of the acidic characteristics. The protonation and deprotonation and also methylation processes in the series of compounds were studied.
How to Cite
Gordienko, O. V.; Kornilov, M. Yu.; Mas'ko, A. N. Chem. Heterocycl. Compd. 2002, 38, 1062. [Khim. Geterotsikl. Soedin. 2002, 1217.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1021296913411
