SYNTHESIS AND ACIDITY OF 5-PHENYLTETRAZOL-2-YLALKANOIC ACIDS AND THE CORRESPONDING 5-(5-PHENYLTETRAZOL-2-YLALKYL)TETRAZOLES

Authors

  • К. А. Есиков St. Petersburg State Technological Institute (Technical University), St. Petersburg 198013
  • В. Ю. Зубарев St. Petersburg State Technological Institute (Technical University), St. Petersburg 198013
  • Е. В. Безклубная St. Petersburg State Technological Institute (Technical University), St. Petersburg 198013
  • А. А. Малин St. Petersburg State Technological Institute (Technical University), St. Petersburg 198013
  • В. А. Островский St. Petersburg State Technological Institute (Technical University), St. Petersburg 198013

Keywords:

ditetrazoles, tetrazoles, tetrazolylalkanoic acids, acidity

Abstract

We have obtained 5-phenyltetrazol-2-ylalkanoic acids and their derivatives containing terminal nitrile, amide, and tetrazol-5-yl groups. Tetrazolylalkanoic acids with two (pKa 4.93) and three (pKa 5.45) bridging methylene groups are weaker acids than the corresponding ditetrazoles (pKa 4.68 and 5.29 respectively). However, the acidity of 5-phenyltetrazol-2-ylacetic acid (pKa 3.12), is higher than acidity of the corresponding ditetrazole (pKa 3.27).

How to Cite
Esikov, K. A.; Zubarev, V. Yu.; Bezklubnaya, E. V.; Malin, A. A.; Ostrovskii, V. A. Chem. Heterocycl. Compd. 2002, 38, 986. [Khim. Geterotsikl. Soedin. 2002, 1127.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1020933900167

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Published

2002-08-25

Issue

No. 8 (2002)

Section

Original Papers