THE REACTION OF 2-AMINOETHYL- AND 3-AMINOPROPYL-SUBSTITUTED HETEROCYCLES WITH 2-FORMYL-1,3-CYCLANEDIONES AND 4-OXO-3,1-BENZOXAZINES
Keywords:
2-aminoethyl- and 3-aminopropyl-substituted heterocycles, 2-formyl-1,3-cyclanediones, dehydroacetic acid, 4-oxo-3,1-benzoxazines, 2-aminomethylene-1,3-cyclanediones, 3-substituted 4(3H)-quinazolinones, monosubstituted N-benzoylanthranilic acid amidesAbstract
The reaction of 2-formyl-1,3-cyclohexanedione, its 5,5-dimethyl, 5-phenyl and 5-(2-furyl) derivatives and of 2-formyl-1,3-indanedione and dehydroacetic acid with histamine, 3-(1-imidazolyl)propylamine, 3-(4-morpholyl)propylamine, 3-(2-pyrrolidon-1-yl)propylamine, 2-(1-piperazinyl)ethylamine, tryptamine, and 2-(aminomethyl)pyridine gave fifteen 2-aminomethylene derivatives. The reaction of these amines with 2-methyl-4-oxo-3,1-benzoxazine gave the 3-substituted 2-methyl-4(3H)-quinazolinones and with 4-oxo-2-phenyl-3,1-benzoxazine the monosubstituted N-benzoylanthranilic acid amides.
How to Cite
Strakovs, A.; Tonkikh, N. N.; Petrova, M.; Ryzhanova, K. V.; Palitis, E. Chem. Heterocycl. Compd. 2002, 38, 449. [Khim. Geterotsikl. Soedin. 2002, 515.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1016087423462
