1-(2-QUINOXALYL)-, 1-[3,5-DI-(TRIFLUOROMETHYL)PHENYL]-, 1-(2-CARBOXYPHENYL)-, AND 1-ETHOXYCARBONYL-4-OXO-4,5,6,7-TETRAHYDROINDAZOLES

Abstract

The corresponding 1-(2-quinoxalyl)-, 1-[3,5-di(trifluoromethyl)phenyl]-, and 1-ethoxycarbonyl-3-methyl-4-oxo-4,5,6,7-tetrahydroindazoles have been obtained from reactions of 2-acetyl-1,3-cyclohexanedione, its 5,5-dimethyl and 5-(2-furyl) derivatives, with 2-hydrazinoquinoxaline, 3,5-di(trifluoromethyl)phenylhydrazine, and ethoxycarbonylhydrazine. On interaction with ethoxycarbonylhydrazine the intermediate 2-[1-(β-ethoxycarbonyl)hydrazino]ethylidene-1,3-cyclohexanediones were also isolated. From the potassium salt of 2-formyldimedone and 2-carboxyphenylhydrazine hydrochloride, 2-(2-carboxyphenyl)hydrazinomethylene-5,5-dimethyl-1,3-cyclohexanedione was obtained, the cyclization of which in ethanol in the presence of HCl led to 1-(2-carboxyphenyl)- and 1-(2-ethoxycarbonylphenyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazole.

How to Cite
Strakova, I.; Strakovs, A.; Petrova, M. Chem. Heterocycl. Compd. 2002, 38, 429. [Khim. Geterotsikl. Soedin. 2002, 494.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1016079221645