SYNTHESIS AND PROPERTIES OF 6,7,8-SUBSTITUTED 2-(4-OXO-3,4-DIHYDRO-2-QUINAZOLINYL)ACETONITRILES

Authors

  • Ю. М. Воловенко Kiev Taras Shevchenko National University, Kiev 01033
  • O. B. Хиля Kiev Taras Shevchenko National University, Kiev 01033
  • Т. А. Воловненко Kiev Taras Shevchenko National University, Kiev 01033
  • T. B. Шокол Kiev Taras Shevchenko National University, Kiev 01033

Keywords:

anthranilic acid, 2-(4-oxo-3,4-dihydro-2-quinazolinyl)acetonitrile, 4-oxo-3,4-dihydroquinazolinone, 3-pyridyl-2-(4-oxo-3,4-dihydro-2-quinazolinyl)acrylonitrile, α-cyanothioacetamide, prototropy, 3-aryl-2-(4-oxo-3,4-dihydro-2-quinazolinyl)acrylonitrile

Abstract

2-(4-Oxo-3,4-dihydro-2-quinazolinyl)acetonitriles have been obtained by the interaction of α-cyanoethylthioiminoacetate with substituted anthranilic acids. Prototropy became apparent in the series of synthesized compounds. Reactions of the 2-(4-oxo-3,4-dihydro-2-quinazolinyl)acetonitriles have been carried out with (hetero)aromatic aldehydes leading to the formation of 3-aryl-2-(4-oxo-3,4-dihydro-2-quinazolinyl)acrylonitriles.

How to Cite
Volovenko, Yu. M.; Khilya, O. V.; Volovnenko, T. A.; Shokol, T. V. Chem. Heterocycl. Compd. 2002, 38, 314. [Khim. Geterotsikl. Soedin. 2002, 350.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1015639404863

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Published

2002-03-25

Issue

No. 3 (2002)

Section

Original Papers