CONVENIENT SYNTHESIS OF 3-(1-CARBOXYALKYL)PYRIDO[2,3-<i>d</i>]PYRIMIDINE-2,4-DIONES

Authors

  • M. Saoud Univ. Abdelmalek Essaadi, Fac. of Sciences-Tetouan, B. P. 2121, Tetouan
  • F. B. Benabdelouahab Univ. Abdelmalek Essaadi, Fac. of Sciences-Tetouan, B. P. 2121, Tetouan
  • F. El Guemmout Univ. Abdelmalek Essaadi, Fac. of Sciences-Tetouan, B. P. 2121, Tetouan
  • A. Romerosa Area de Quimica Inorganica, Facultad de Ciencias, Universidad de Almeria, 04071, Almeria

Keywords:

amino acids, pyrido[2,3-d]pyrimidine, pyridinecarboxylic acids

Abstract

Cheap and safety synthetic route to obtain 3-(1-carboxyalkyl)pyrido[2,3-d]-pyrimidinediones (carboxyalkyl = –CHRCO2H; R = H; CH2; CH2Ph; Ph; CH2(C3H3N2); (CH2)2CO2H; CH2CO2H) starting from 2,3-pyridinedicarboxylic acid is described. A process scheme consistent with empirical observations is proposed.

How to Cite
Saoud, M.; Benabdelouahab, F. B.; El Guemmout, F. ; Romerosa, A. Chem. Heterocycl. Compd. 2002, 38, 306. [Khim. Geterotsikl. Soedin. 2002, 342.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1015635303954

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Published

2002-03-25

Issue

No. 3 (2002)

Section

Original Papers