SYNTHESES OF NEW CARBONYL DERIVATIVES FROM α-HALOHETARYL KETONES

Authors

  • D. Gavriliu Faculty of Chemistry, Org. Chem. Dept., University of Bucharest, 90-92 Panduri Road, 76233
  • T. Loloiu Faculty of Pharmacy, Org. Chem. Dept., University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia street, Bucharest
  • A. Nicolae Faculty of Chemistry, Org. Chem. Dept., University of Bucharest, 90-92 Panduri Road, 76233
  • G. Loloiu Faculty of Chemistry, Org. Chem. Dept., University of Bucharest, 90-92 Panduri Road, 76233
  • O. Maior Faculty of Chemistry, Org. Chem. Dept., University of Bucharest, 90-92 Panduri Road, 76233

Keywords:

2-ω-bromoacetylphenoxathiin, 2-ω-bromophenoxathiin 10,10-dioxide, glyoxals, α-halohetaryl ketones, N-ylides, S-ylides, cyclization, Kröhnke reaction

Abstract

The Kröhnke reaction of 2-ω-bromoacetylphenoxathiin and 2-ω-bromophenoxathiin 10,10-dioxide, through N-ylide and S-ylide intermediates, leading to the corresponding glyoxals, was described. The condensation reaction of 2-ω-bromoacetylphenoxathiin with aromatic o-hydroxy aldehydes and further cyclization to new furan derivatives was also performed. The new compounds were characterized through elemental analysis and spectral data (IR, 1H NMR and 13C NMR).

How to Cite
Gavriliu, D.; Loloiu, T.; Nicolae, A.; Loloiu,G.; Maior, O. Chem. Heterocycl. Compd. 2002, 38, 242. [Khim. Geterotsikl. Soedin. 2002, 265.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1015307813291

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Published

2002-02-25

Issue

No. 2 (2002)

Section

Original Papers