ANNELATION OF THE PYRROLE TO THE STEROID SKELETON USING THE TROFIMOV REACTION

Authors

  • А. M. Васильцов A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk 664033
  • A. Б. Зайцев A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk 664033
  • A. И. Михалева A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk 664033
  • E. Ю. Шмидт A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk 664033
  • А. В. Афонин A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk 664033

Keywords:

acetylene, N-vinylpyrroles, ketosteroids, Trofimov reaction, KOH–DMSO system

Abstract

The product of annelation of the N-vinyl pyrrole ring with steroid skeleton of 5-cholestene was obtained in a single regioselective step by the reaction of 5-cholesten-3-one oxime with acetylene in KOH-DMSO by the Trofimov reaction.

How to Cite
Vasil'tsov, A. M.; Zaitsev, A. B.; Mikhaleva, A. I.; Shmidt, E. Yu.; Afonin, A. V. Chem. Heterocycl. Compd. 2002, 38, 60. [Khim. Geterotsikl. Soedin. 2002, 66.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1014803325701

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Published

2002-01-25

Issue

No. 1 (2002)

Section

Original Papers