PALLADIUM-CATALYZED INTER- AND INTRAMOLECULAR HYDROAMINATION OF METHYLENECYCLOPROPANES WITH AMINES

Authors

  • I. Nakamura Research Center for Sustainable Materials Engineering, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai 980-8578
  • H. Itagaki Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578
  • Y. Yamamoto Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578

Keywords:

azepane derivative, methylenecyclopropane, nitrogen pronucleophile, hydroamination, palladium catalyst

Abstract

The inter- and intramolecular addition of nitrogen pronucleophiles to methyle-necyclopropanes proceeds smoothly in the presence of palladium catalyst, giving the corresponding hydroamination products in good to excellent yields. The reac-tion mainly proceeds through cleavage of a distal bond of methylenecyclo-propanes.

How to Cite
Nakamura, I.; Itagaki, H.; Yamamoto, Y. Chem. Heterocycl. Compd. 2001, 37, 1532. [Khim. Geterotsikl. Soedin. 2001, 1684.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1014513411239

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Published

2001-12-25

Issue

No. 12 (2001)

Section

Original Papers