Aminolysis of 5-Phenyl-2-tetrazolylacetic Acid Ethyl Ester

Authors

  • С. М. Путис St. Petersburg State Technological Institute (Technical University), Saint Petersburg 198
  • B. Ю. Зубарев St. Petersburg State Technological Institute (Technical University), Saint Petersburg 198
  • B. C. Поплавский St. Petersburg State Technological Institute (Technical University), Saint Petersburg 198013
  • B. А. Островский St. Petersburg State Technological Institute (Technical University), Saint Petersburg 198013

Keywords:

5-phenyl-2-tetrazolylacetamides, 5-phenyl-2-tetrazolylacetic acid ethyl ester, aminolysis

Abstract

It was shown using 5-phenyl-2-tetrazolylacetic acid ethyl ester as an example that aminolysis is a competitive method of synthesizing primary amides. The efficiency of aminolysis by primary amines is linked to the basicity of the initial amine. Highly basic amines display more high reactivity independent of the spatial structure of the substituent. Reaction of the investigated ester with secondary amines occurs ambiguously.

How to Cite
Putis, S. M.; Zubarev, V. Yu.; Poplavskii, V. S.; Ostrovskii, V. A. Chem. Heterocycl. Compd. 2001, 37, 698. [Khim. Geterotsikl. Soedin. 2001, 759.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1011909127876

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Published

2001-06-25

Issue

No. 6 (2001)

Section

Original Papers