REACTION OF 1,3-DIOXANES WITH ACETONE CYANOHYDRIN

Authors

  • В. В. Кузнецов A. V. Bogatsky Physico-chemical Institute, National Academy of Sciences of Ukraine, 270080 Odessa
  • Ю. Э. Брусиловский A. V. Bogatsky Physico-chemical Institute, National Academy of Sciences of Ukraine, 270080 Odessa

Keywords:

1,3-amino alcohols, acetone cyanohydrin, 5,6-dihydro-1,3-oxazines, 1,3-dioxanes

Abstract

The reaction of 4-phenyl- and 4,4-dimethyl-1,3-dioxanes with acetone cyanohydrin leads to hydrolytically unstable 2-(1-hydroxy-1-methylethyl)-5,6-dihydro-1,3-oxazines, which are readily saponified in alkaline medium to the corresponding 1,3-amino alcohols.

How to Cite
Kuznetsov, V. V.; Brusilovskii, Yu. E. Chem. Heterocycl. Compd. 2001, 37, 574. [Khim. Geterotsikl. Soedin. 2001, 626.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1011652404696

Published

2001-05-25

Issue

Section

Original Papers