Electrophilic substitution in benzo[<i>b</i>]furo[2,3-<i>c</i>]pyridines: nitration, acylation

Authors

  • C. B. Толкунов L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk
  • М. Н. Кальницкий L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk
  • B. И. Дуленко L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk
  • C. Н. Лящук L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk

Abstract

It has been shown that the nitration and acylation of substituted benzo[b]furo[2,3-c]pyridines proceeds exclusively at position 6 of the benzene ring. If position 6 is blocked by a substitutnt, the product of monosubstitution at the C(8) atom is formed. The molecules that were investigated have been calculated in the MNDO approximation.

How to Cite
Tolkunov, S. V.; Kal'nitskii, M. N.; Dulenko, V. I.; Lyashchuk, S. N. Chem. Heterocycl. Compd. 1995, 31, 615. [Khim. Geterotsikl. Soedin. 1995, 694.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01166340

Published

1995-05-25

Issue

Section

Original Papers