Investigation of the stereodirection of the Ritter reaction. Crystalline and molecular structure of N-(2-phenethyl)-4-methylpiperid-4-ol and N-(2-phenethyl)-4-methyl-4-acetamidopiperidine

Authors

  • B. O. Мартиросян A. D. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Republic of Armenia, 375014 Yerevan
  • А. А. Карапетян A. D. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Republic of Armenia, 375014 Yerevan
  • P. C. Вартанян A. D. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Republic of Armenia, 375014 Yerevan
  • Ю. T. Стручков A. D. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Republic of Armenia, 375014 Yerevan

Abstract

The stereodirection of the Ritter reaction of N-(2-phenethyl)-4-methylpiperid-4-ol to the corresponding amide has been studied. X-ray analysis has shown that the reaction occurs with retention of the configuration about atom C4 of the piperidine ring. Attempts are made to explain the stereodirection of the direction.

How to Cite
Martirosyan, V .O.; Karapetyan, A. A.; Vartanyan, R. S.; Struchkov, Yu. T. Chem. Heterocycl. Compd. 1994, 30, 1206. [Khim. Geterotsikl. Soedin. 1994, 1391.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01184886

Published

1994-10-25

Issue

Section

Original Papers