CONVENIENT MODIFICATION OF THE LEIMGRUBER-BATCHO INDOLE SYNTHESIS: REDUCTION OF 2-NITRO-β-PYRROLIDINOSTYRENES BY THE FeCl<sub>3</sub>–ACTIVATED CARBON–N<sub>2</sub>H<sub>4</sub>·H<sub>2</sub>O SYSTEM

Authors

  • И. В. Тайдаков G. S. Petrov Institute of Plastics
  • Т. Я. Дутова State Research Center for Antibiotics
  • Е. Н. Сидоренко State Research Center for Antibiotics
  • С. С. Красносельский Peoples' Friendship University of Russia

DOI:

https://doi.org/10.1007/1799

Keywords:

enamines, indoles, β-dialkylamino-2-nitrostyrenes, Leimgruber-Batcho synthesis, reductive cyclization

Abstract

A new catalytic system containing ferric chloride, activated carbon, and hydrazine has been proposed for the reductive cyclization of β-dialkylamino-2-nitrostyrenes to give the corresponding indoles (Leimgruber-Batcho synthesis). Various substituted indoles may be obtained in high yield under these conditions.

How to Cite
Taydakov, I. V.; Dutova, T. Ya.; Sidorenko, E. N.; Krasnoselsky S. S. Chem. Heterocycl. Compd. 2011, 47(4), 425. [Khim. Geterotsikl. Soedin. 2011, 521.]

For this article in the English edition see DOI 10.1007/s10593-011-0776-2

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Published

2014-05-20

Issue

No. 4 (2011)

Section

Original Papers