SYNTHESIS OF HETEROCYCLES ON THE BASIS OF ARYLATION PRODUCTS OF UNSATURATED COMPOUNDS. 19. ARYLATION OF 2 ACETYLTHIO- PHENE AND THE SYNTHESIS OF 2-(5-ARYL-2-THIENYL)-4-QUINOLINECARBOXYLIC ACIDS

Authors

  • В. С. Матийчук Ivan Franko Lviv National University
  • Н. Д. Обушак Ivan Franko Lviv National University
  • Р. З. Лытвын Ivan Franko Lviv National University
  • Ю. И. Горак Ivan Franko Lviv National University

DOI:

https://doi.org/10.1007/2779

Keywords:

2-acetyl-5-arylthiophenes, 2-acetylthiophene, 4-quinolinecarboxylic acid derivatives, arylation, Meerwein reaction, Pfitzinger reaction

Abstract

The reaction of 2‑acetylthiophene with acetylthiophene with arenediazonium chlorides in the presence of cupric chloride as catalyst gives 2‑acetyl-5-arylthiophenes. These products react with 5-chloro- and 5-bromoisatins to give 6-chloro- and 6-bromo-substituted 2-(5-aryl-2-thienyl)-4-quinolinecarboxylic acids.

How to Cite
Matiychuk, V. S.; Obushak, N. D.; Lytvyn, R. Z.; Horak, Yu. I. Chem. Heterocycl. Compd. 2010, 46, 50. [Khim. Geterotsikl. Soedin. 2010, 61.]

For this article in the English edition see DOI 10.1007/s10593-010-0468-3

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Published

2015-11-25

Issue

No. 1 (2010)

Section

Original Papers