ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED 4,5-DIHYDROPYRROLES BY REACTIONS OF ARYLGLYOXALS, β-DICARBONYL COMPOUNDS, AND AROMATIC AMINES
Authors
Надежда Н. Колос
V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
Сергей А. Карпань
V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
Ирина В. Омельченко
Scientific-Technological Complex ''Institute of Monocrystals", National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
Наталья В. Чечина
V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
Федор Г. Яременко
Scientific-Technological Complex ''Institute of Monocrystals", National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
A multicomponent reaction of arylglyoxal hydrates, acetylacetone or acetoacetic ester, aniline or its 3(4)-substituted analogs in 1:1:2 ratio occurred upon stirring in methanol, giving 4-arylamino-5-hydroxypyrroline derivatives containing 4,5-dihydroxypyrrolines as impurities.
Author Biographies
Надежда Н. Колос, V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
кафедра органической химии, профессор
Сергей А. Карпань, V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
кафедра органической химии, магистр
Ирина В. Омельченко, Scientific-Technological Complex ''Institute of Monocrystals", National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
к.х.н., ст. научный сотрудник
Наталья В. Чечина, V. N. Karazin Kharkiv National University,
4 Svobody Sq., Kharkiv 61022, Ukraine
кафедра органической химии, аспирант
Федор Г. Яременко, Scientific-Technological Complex ''Institute of Monocrystals", National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine