SYNTHESIS AND SOME CHEMICAL PROPERTIES OF 2-CYANO-4-PYRONE

Authors

  • Дмитрий Л. Обыденнов Institute of Natural Sciences and Mathematics of the Ural Federal University named after the first President of Russia B. N. Yeltsin, 51 Lenina Ave., Yekaterinburg 620000
  • Aлександра И. Суслова Institute of Natural Sciences and Mathematics of the Ural Federal University named after the first President of Russia B. N. Yeltsin, 51 Lenina Ave., Yekaterinburg 620000
  • Вячеслав Я. Сосновских Institute of Natural Sciences and Mathematics of the Ural Federal University named after the first President of Russia B. N. Yeltsin, 51 Lenina Ave., Yekaterinburg 620000

DOI:

https://doi.org/10.1007/5415

Keywords:

carbamoylated enaminones, 2-cyano-4-pyrones, 2-heteroaryl-4-hydroxypyridines, 2-heteroaryl-4-pyrones, 4-oxo-1, 4-dihydropyridine-3-carboxamides, pyrazoles

Abstract

2-Cyano-4-pyrone obtained from comanic acid ethyl ester reacts with amines and hydrazines with the opening of the pyrone ring and substitution of the cyano group to form carbamoylated aminoenones (yields 62–87%) and pyrazolylacetic acid hydrazides. The reactions of 2-cyano-4-pyrone with hydroxylamine or sodium azide involve exclusively the cyano group, which makes it possible to obtain 2-heteroaryl-4-pyrones and 2-heteroaryl-4-hydroxypyridines.

Authors: Dmitrii L. Obydennov*, Aleksandra I. Suslova, Vyacheslav Ya. Sosnovskikh

Author Biography

Дмитрий Л. Обыденнов, Institute of Natural Sciences and Mathematics of the Ural Federal University named after the first President of Russia B. N. Yeltsin, 51 Lenina Ave., Yekaterinburg 620000

Дмитрий Львович Обыденнов

доцент кафедры органической химии и высокомолекулярных соедиединений ИЕНиМ УрФУ

Downloads

Published

2020-02-28

Issue

Vol. 56 No. 2 (2020)

Section

Original Papers