<i>N</i>-(ORGANYLMETHYLIDENE)BIS(CHLOROMETHYLIDENE)THIOMORPHOLIN-4-AMINES AND –SELENOMORPHOLIN-4-AMINES
DOI:
https://doi.org/10.1007/622Keywords:
aldehydes, hydrazones, selenomorpholin-4-amine, thiomorpholin-4-amineAbstract
The reaction of (2E,6E)-bis(chloromethylidene)thiomorpholin-4-amine and -selenomorpholin-4-amine with propionaldehyde, benzaldehyde, or 4-pyridinecarbaldehyde in benzene in the presence of catalytic amounts of formic acid gave the corresponding hydrazones, the N-(organylmethylidene)-(2E,6E)bis(chloromethylidene)thiomorpholin-4-amines and -selenomorpholin-4-amines, as trans isomers. The structure of the hydrazones was confirmed by 1H and 13C NMR, as well as 2D 1H–1H NOESY experiments.
Authors: A. V. Martynov, N. A. Makhaeva, and S. V. Amosova.
English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (5), pp 797-801