HETEROPHASE N-AMINOMETHYLATION OF 5-ARYLIDENEPSEUDOTHIOHYDANTOINS BY ARYLAMINES AND AQUEOUS FORMALDEHYDE IN AROMATIC SOLVENTS: EFFECT OF SUBSTITUENTS IN THE HETEROCYCLIC SUBSTRATE AND THE ARYL AMINE ON THE EFFICIENCY OF THE PROCESS

Authors

  • С. М. Рамш St. Petersburg State Technical University, St. Petersburg 198013
  • Н. Л. Медведский St. Petersburg State Technical University, St. Petersburg 198013
  • С. О. Урюпов St. Petersburg State Technical University, St. Petersburg 198013

DOI:

https://doi.org/10.1007/7911

Keywords:

2-amino-5-arylidene-1, 3-thiazol-4(5H)-ones (5-arylidenepseudothiohydantoins), 3-aryl-7-arylidene-3, 4-dihydro-2H-[1, 3]thiazolo[3, 2-a][1, 3, 5]triazin-6(7H)-ones, aminomethylation, synthesis

Abstract

We have obtained a series  of  3-aryl-7-arylidene-3,4-dihydro-2H-[1,3]thiazolo[3,2-a][1,3,5]triazin-6(7H)-ones by means of  heterophase  aminomethylation of 2-amino-5-arylidene-1,3-thiazol-4(5H)-ones with aqueous formaldehyde  and aromatic amines in benzene or  toluene. We explain the effect of substituents in the heterocyclic substrate and  the  aryl amine on the efficiency of the process within a detailed scheme for one of the possible aminomethylation reaction routes.

How to Cite
Ramsh, S. M.; Medvedskiy, N. L.; Uryupov, S. O.  Chem. Heterocycl. Compd. 2006, 42, 948. [Khim. Geterotsikl. Soedin. 2006, 1095.]

For this article in the English edition see DOI 10.1007/s10593-006-0185-0

 

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Published

2023-07-26

Issue

No. 7 (2006)

Section

Original Papers