BASICITY OF 2-PHENYL-5-R-1,3,4-OXADIAZOLES

Authors

  • Р. Е. Трифонов St. Petersburg State Technical University, St. Petersburg 190013
  • В. А. Островский St. Petersburg State Technical University, St. Petersburg 190013

DOI:

https://doi.org/10.1007/7987

Keywords:

1, 3, 4-oxadiazoles, weak bases, basicity, UV spectroscopy, acidity function, electronic substituent constants

Abstract

We have studied the basicity of 2-phenyl-5-R-1,3,4-oxadiazoles (R = H, Me, CH2Ph, t-Bu, CH2Cl, CCl3, CF3) in aqueous sulfuric acid solutions.  These compounds are weak organic bases (pKBH + is -1.8 to -5.2). The values of pKBH+ determined on the H0 and X acidity function scales agree well with each other. The substituent at the 5 position has a substantial effect on the basicity of the 1,3,4-oxadiazole ring.

How to Cite
Trifonov, R. E.; Ostrovskii, V. A.  Chem. Heterocycl. Compd. 2006, 42, 657. [Khim. Geterotsikl. Soedin. 2006, 348.]

For this article in the English edition, see DOI 10.1007/s10593-006-0142-y

 

Downloads

Published

2023-08-22

Issue

No. 5 (2006)

Section

Original Papers