TAUTOMERISM OF THE THIOAMIDE GROUP IN 4-METHYL-7-NITRO-2,3,4,5-TETRAHYDRO-1,5-BENZODIAZEPINE-2-THIONE

Authors

  • Р. Янчене Institute of Biochemistry, Vilnius LT-2600
  • З. Стумбрявичюте Institute of Biochemistry, Vilnius LT-2600
  • Л. Плечкайтене Institute of Biochemistry, Vilnius LT-2600
  • Б. Пуоджюнайте Institute of Biochemistry, Vilnius LT-2600

Keywords:

4-methyl-7-nitro-2,3,4,5-tetrahydro-1,5-benzodiazepine-2-thione, thione–thiol tautomers

Abstract

When 4-methyl-7-nitro-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one were reacted with phosphorus pentasulfide, the corresponding benzodiazepine-2-thione and its thiol tautomer were formed, which via the 2-methylmercapto derivative were converted to 4-(2-acetylhydrazino)-2-methyl-8-nitro-2,3-dihydro-1H-1,5-benzodiazepine.

How to Cite
Janciene, R.; Stumbreviciute, Z.; Pleckaitiene, L.; Puodziunaite, B. Chem. Heterocycl. Compd. 2002, 38, 738. [Khim. Geterotsikl. Soedin. 2002, 837.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1019933722956

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Published

2002-06-25

Issue

No. 6 (2002)

Section

Original Papers