Bromination of 4-substituted thiazolylhydrazones

Abstract

4-Phenyl- and 4-methylthiazolylhydrazones were brominated in chloroform and acetic acid. The use of 1.5 equivalents of bromine led to the exclusive formation of the 5-halo derivatives. Effects of substituents on the thiazole ring and of the hydrazone fragment aromatic ring on the course of the reaction were discovered.

How to Cite
Denisova, A. B., Andronnikova, G. P. Chem. Heterocycl. Compd. 1995, 31, 863. [Khim. Geterotsikl. Soedin. 1995, 991.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01170750