New method of synthesis of D,L-5-oxoproline

Authors

  • Г. А. Еpмакова All-Russian Scientific Center for the Safety of Biologically Active Substances (VNTs BAV), Kupavna, Moscow Oblast, 142450
  • С. Я. Скачилова All-Russian Scientific Center for the Safety of Biologically Active Substances (VNTs BAV), Kupavna, Moscow Oblast, 142450
  • Н. И. Юрченко All-Russian Scientific Center for the Safety of Biologically Active Substances (VNTs BAV), Kupavna, Moscow Oblast, 142450

Abstract

A new method was proposed for synthesis of D,L-5-oxoproline from N-acetyl-L-glutamic acid in weakly acid medium in the presence of water, and hydrolysis of an acetyl and cyclization and total racemization of the acid simultaneously take place. The advantage of the method is the possibility of obtaining two individual amino acids with high yields in one chemical process using L-glutamic acid.

How to Cite
Ermakova, G. A.; Skachilova, S. Ya.; Yurchenko, N. I. Chem. Heterocycl. Compd. 1995, 31, 33. [Khim. Geterotsikl. Soedin. 1995, 39.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01171286

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Published

1995-01-25

Issue

No. 1 (1995)

Section

Original Papers