THIRTY YEARS OF PYRIMIDINE CHEMIST`RY IN THE LABORATORY OF ORGANIC CHEMISTRY AT THE WAGENINGEN AGRICULTURAL UNIVERSITY, THE NETHERLANDS

Abstract

In this review attention is paid to two topics, which were of great interest to us during 30 years of studies in pyrimidine chemistry in our laboratory. First, the development of our concepts of the ANRORC processes, which occur in ring transformation reactions. Secondly the intra- and intermolecular inverse Diets—Alder reactions in which the pyrimidine ring acts as the electron-poor diazadiene system. Their use in synthetic chemistry is illustrated and evidence is presented, based on experiments and molecular mechanics calculations that in intramolecular Diets—Alder reactions the geometry of the side chain plays a vital role.

How to Cite
van der Plas, H. C. Chem. Heterocycl. Compd. 1994, 30, 1427. [Khim. Geterotsikl. Soedin. 1994, 1649.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01172867