4-Dialkyldithiocarbamoyl-5-nitropyrimidines. Synthesis, structure, properties

Authors

  • B. А. Макаров Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815
  • А. Л. Седов Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815
  • М. П. Немерюк Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815
  • Н. П. Соловьева Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815
  • O. C. Анисимова Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815
  • T. C. Сафонова Center for the Chemistry of Medicinals, All-Russian Chemico-Pharmaceutical Scientific Research Institute, Moscow 119815

Abstract

The reaction of 4-chloro-5-nitropyrimidines with sodium dialkyldithiocarbamates gives the corresponding 4-dialkyldithiocarbamoyl derivatives. On heating these derivatives the nitro group is displaced and disulfides are formed at position 5 of the pyrimidine ring. Transformation to 1,3-dithiolo[4,5-d]pyrimidines has been demonstrated.

How to Cite
Makarov, V. A.; Sedov, A .L.; Nemeryuk, M. P.; Solov'eva, N. P.; Anisimova, O. S.; Safonova, T. S. Chem. Heterocycl. Compd. 1994, 30, 1231. [Khim. Geterotsikl. Soedin. 1994, 1420.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01184891

Downloads

Published

1994-10-25

Issue

No. 10 (1994)

Section

Original Papers