DOMINO REACTIONS IN THE SYNTHESIS OF BENZOTHIENO[2,3-<i>c</i>]PYRIDINES. NEW ONE-POT METHOD OF PREPARING 2-([1]BENZOTHIENO[2,3-<i>c</i>]PYRIDIN-1-YL)BENZOIC ACIDS AND 8,13b-DIHYDRO[1]BENZOTHIENO[2',3':3,4]PYRIDO[2,1-<i>a</i>]ISOINDOL-5(7<i>H</i>)-ONES

Authors

  • В. С. Толкунов L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry, National Academy of Sciences of Ukraine
  • А. Б. Ересько L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry, National Academy of Sciences of Ukraine
  • А. И. Хижан L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry, National Academy of Sciences of Ukraine
  • А. В. Мазепа A. V. Bogatskii Physicochemical Institute, National Academy of Sciences of Ukraine
  • Г. В. Паламарчук NTK "Institute of Monocrystals", National Academy of Sciences of Ukraine
  • О. В. Шишкин NTK "Institute of Monocrystals", National Academy of Sciences of Ukraine; Kharkov V. N. Karazin National University
  • С. В. Толкунов L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/1223

Keywords:

2-([1]benzothieno[2, 3-c]pyridin-1-yl)benzoic acids, 8, 13b-dihydro[1]benzothieno[2', 3', 3, 4]pyrido[2, 1-a]isoindol-5(7H)-ones, 2-[3-oxo-4-(phenylsulfanyl)butyl]-1, 3-isoindolinediones, cyclization, domino reaction, polyphosphoric acid

Abstract

A series of previously unknown 2-([1]benzothieno[2,3-c]pyridin-1-yl)benzoic acids and 8,13b-dihydro-[1]benzothieno[2',3':3,4]pyrido[2,1-a]isoindol-5(7H)-ones has been synthesized using domino reactions, taking place at the cyclization of 2-[3-oxo-4-(phenylsulfanyl)butyl]-1,3-isoindolinediones in polyphosphoric acid.

Authors: V. S. Tolkunov, A. B. Eres'ko, A. I. Khizhan, A. V. Mazepa, G. V. Palamarchuk, O. V. Shishkin, and S. V. Tolkunov.

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (4), pp 666-671

http://link.springer.com/article/10.1007/s10593-012-1041-z

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Published

2013-11-22

Issue

No. 4 (2012)

Section

Original Papers