NEW METHOD FOR THE SYNTHESIS OF 2-PHENYLPROLINE AND ITS DERIVATIVES

Authors

  • А. O. Маpтиросян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia
  • C. П. Гаспарян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia
  • B. E. Oгaнесян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia
  • M. B. Алексaнян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia
  • M. H. Никищенко A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia
  • Г. Ш. Бабаян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia

DOI:

https://doi.org/10.1007/171

Keywords:

amino acids, phenylproline, intramolecular cyclization, phase-transfer catalysis

Abstract

A new method has been developed for the synthesis of 2-phenylproline and its derivatives by intramolecular cyclization of the corresponding derivatives of N-(3-chloro- or 1-oxo-3-chloropropyl)-a-phenylglycine under phase transfer catalysis conditions.

Authors: A. O. Martirosyan, S. P. Gasparyan, V. E. Oganesyan, Sh. L. Mndzhoyan, M. V. Aleksanyan, M. N. Nikishchenko, and G. Sh. Babayan.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (4), pp 416-420

http://link.springer.com/article/10.1007/BF02269538

 

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Published

2013-01-15

Issue

No. 4 (2000)

Section

Original Papers