DIARYL-SUBSTITUTED POLYETHERS WITH ACETOACETANILIDE FRAGMENT IN THE SYNTHESIS OF DIHYDROPYRIMIDINE-CONTAINING PODANDS

Authors

  • Е. С. Радионова Ural Federal University named after the First President of Russia B. N. Yeltsin
  • Ю. А. Титова Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences
  • М. Л. Исенов I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences
  • О. В. Федорова Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences
  • Г. Л. Русинов Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences
  • В. Н. Чарушин Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1762

Keywords:

acetoacetanilide-containing podands, acetyl ketene, aminoaryl-substituted podands, dihydropyrimidine-containing podands, Biginelli reaction, ultrasonication

Abstract

The interaction of ortho-aminoaryl polyethers, derivatives of mono-, di-, and triethylene glycol, with acetyl ketene, generated from 2,2,6-trimethyl-4H-1,3-dioxin-4-one produced acetoacetanilide- containing podands. 2,2,6-Trimethyl-4H-1,3-dioxin-4-one reacted with aminoaryl-substituted podands containing a short polyether chain (1-2 atoms) in toluene medium without catalyst. Acetoacetanilide- containing podands with longer polyether chains could be obtained by using triethylamine or acetic acid as catalyst. Acetoacetanilide-containing podands were used in the Biginelli reaction as СН-active components.

How to Cite
Radionova, E. S.; Titova, Yu. A.; Isenov, M. L.; Fedorova, O. V.; Rusinov, G. L.; Charushin, V. N. Chem. Heterocycl. Compd. 2014, 50, 998. [Khim. Geterotsikl. Soedin. 2014, 1083.]

For this article in the English edition see DOI 10.1007/s10593-014-1555-7

Author Biographies

Е. С. Радионова, Ural Federal University named after the First President of Russia B. N. Yeltsin

Елена Сергеевна Радионова

Химико-технологический институт, кафедра органической химии,аспирантка первого года обучения

Ю. А. Титова, Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

Юлия Алексеевна ТитоваЛаборатория гетероциклических соединений, к.х.н., младший научный сотрудник

М. Л. Исенов, I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

Максим Львович ИсеновЛаборатория гетероциклических соединений, младший научный сотрудник

О. В. Федорова, Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

Ольга Васильевна ФедороваЛаборатория гетероциклических соединений, к.х.н., старший научный сотрудник

Г. Л. Русинов, Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

Геннадий Леонидович РусиновЛаборатория гетероциклических соединений, к.х.н., ведущий научный сотрудник

В. Н. Чарушин, Ural Federal University named after the First President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences

Валерий Николаевич Чарушин

директор института Института органического синтеза им. И. Я. Постовского, Уральского отделения Российской академии наук (ИОС УрО РАН), академик

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Published

2014-08-08

Issue

No. 7 (2014)

Section

Original Papers