INTERACTION OF AMINOQUINOLINES WITH UNSATURATED CARBOXYLIC ACIDS. 1. SYNTHESIS OF N-QUINOLYL-β-ALANINES AND THEIR BIOLOGICAL ACTIVITY

Authors

  • Z. J. Beresnevičius Kaunas University of Technology
  • V. Viliūnas Kaunas University of Technology
  • K. Kantminienė Kaunas University of Technology

DOI:

https://doi.org/10.1007/180

Keywords:

aminoquinolines, N-quinolyl-β-alanines, hydrazides, biological activity

Abstract

N-Quinolyl-β-alanines, α-methyl- and β-methyl-N-quinolyl-β-alanines were prepared by reaction of aminoquinolines and acrylic, methacrylic and crotonic acids. The corresponding hydrazides and benzylidenehydrazides were obtained. 4-Aminoquinoline with unsaturated acids in water gave betaines. Biological activity of sodium salts of β-alanines were investigated.

Also published in Chemistry of Heterocyclic Compounds, 2000, 36 (4), pp 432-438

http://link.springer.com/article/10.1007/BF02269541

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Published

2013-01-22

Issue

No. 4 (2000)

Section

Original Papers