REACTIONS OF (<i>S</i>)-(4-NITROPHENYL)[(4<i>S</i>)-2-OXO-1,3-OXAZOLIDIN-4-YL]METHYL METHANESULFONATE WITH ALKALI METAL HALIDES AND LITHIUM HYDROXIDE. SYNTHESIS OF [(2<i>R</i>,3<i>R</i>)-3-(4-NITROPHENYL)AZIRIDIN-2-YL]METHANOL
DOI:
https://doi.org/10.1007/245Keywords:
aziridine, oxazolidin-2-one, recyclizationAbstract
The formation [(2R,3R)-3-(4-nitrophenyl)aziridin-2-yl]methanol and 2-oxazolidine ring opening occurrred in the reaction of (S)-(4-nitrophenyl)[(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl methanesulfonate with lithium hydroxide in aqueous dioxane or under phase transfer catalysis conditions.
Authors: M. Madesclaire, P. Coudert, F. Leal, S. Tarrit, Yu. V. Zaitseva, and V. P. Zaitsev.
English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (8), pp 1103-1107