СИНТЕЗ ПЕРВЫХ 13-НИТРОАРИЛЬНЫХ ПРОИЗВОДНЫХ 8-АЦЕТОНИЛБЕРБЕРИНА

Олег Н. Буров; Сергей В. Курбатов; Павел Г. Морозов; Михаил Е. Клецкий; Артем В. Татаров

doi:10.1007/2569

Authors

Олег Н. Буров Southern Federal University, 7 Zorge St., Rostov-on-Don 344090
Сергей В. Курбатов Southern Federal University, 7 Zorge St., Rostov-on-Don 344090
Павел Г. Морозов Southern Federal University, 7 Zorge St., Rostov-on-Don 344090
Михаил Е. Клецкий Southern Federal University, 7 Zorge St., Rostov-on-Don 344090
Артем В. Татаров Southern Federal University, 7 Zorge St., Rostov-on-Don 344090

DOI:

https://doi.org/10.1007/2569

Keywords:

berberine, nitroarene, nucleophilic aromatic substitution

Abstract

For the first time a method for the synthesis of 8-acetonylberberine 13-nitroaryl derivatives has been developed comprising a one-pot reaction of berberine, acetone, and neutral aromatic electrophiles (picryl chloride, 4-chloro-7-nitrobenzofurazan, 4-chloro-5,7-dinitrobenzofurazan). It was found that the reaction of 8-acetonylberberine with these chloronitroarenes does not lead to the formation of the target compounds.

How to Cite
Burov, O. N.; Kurbatov, S. V.; Morozov, P. G.; Kletskii, M. E.; Tatarov, A. V. Chem. Heterocycl. Compd. 2015, 51, 772. [Khim. Geterotsikl. Soedin. 2015, 51, 772.]

For this article in the English edition see DOI 10.1007/s10593-015-1774-6

Author Biographies

Олег Н. Буров, Southern Federal University, 7 Zorge St., Rostov-on-Don 344090

Олег Николаевич Буров

Старший научных сотрудник кафедры химии природных и высокомолекулярных соединений химического факультета ЮФУ