UNUSUAL AMINO ACIDS. 5. SYNTHESIS OF 3,5-DIOXOPYRAZOLIDINE DERIVATIVES
DOI:
https://doi.org/10.1007/261Keywords:
3, 5-dioxopyrazolidines, malonic acid, monohydrazides of 2-R-4-methyl-4-cyclohexene-1, 1-dicarboxylic acidsAbstract
Monohydrazides of 2-R-4-methyl-4-cyclohexene-1,1-dicarboxylic acids react with trifluoroacetic acid anhydride to give 4-substituted 3,5-dioxopyrazolidines, with phosphorus trichloride to give 4‑(2‑R‑5‑chloro-4‑methylcyclohexane)-3,5-dioxopyrazolidines, and with acetic anhydride to give 4‑(2‑R‑4-methyl-4-cyclohexene)-3,5-diacetoxypryazoles.
Authors: D. Zicane, Z. Tetere, I. Rijkure, M. V. Petrova, E. Gudriniece, and U. Kalejs.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (7), pp 792-795