CYCLIZATION OF N-(2,4,6-TRIMETHYLPHENYL)-β-ALANINES

Authors

  • В. Мицкявичюс Kaunas Technological University
  • А. Патупайте Kaunas Technological University

DOI:

https://doi.org/10.1007/264

Keywords:

dihydropyrimidinediones, N-substituted beta-alanines, 4-carboxy-2-pyrrolidinones, 4(1H) tetrahydropyridones, condensation

Abstract

Reaction of 2,4,6-trimethylaniline with acrylic and itaconic acids gives the corresponding N-substituted β-alanines which can be converted to derivatives of tetrahydropyridone, dihydropyrimidinedione, and 4 carboxy-2-pyrrolidinone. Bromination of the aromatic substituent in the synthesized heterocycles has been carried out.

Authors: V. Mickevicius and A. Patupaite.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (7), pp 837-840

http://link.springer.com/article/10.1007/BF02256919

Published

2013-02-06

Issue

Section

Original Papers