NH-1,2,3-TRIAZOLES: SYNTHESIS AND REACTIONS WITH ELECTROPHILIC AGENTS

Abstract

A renewal of interest in the chemistry of 1,2,3-triazoles has occurred since the beginning of the 21^st century. The application of metal catalysis and organocatalysis to the classical Huisgen^1–5 and Dimroth reactions^6,7 has provided access to a wide range of 1,2,3-triazole derivatives for a variety of chemical and biological studies. This, in turn, has resulted in the use of these compounds in biological and medicinal chemistry, technology, and medicine.^8,9 In this report we focus on using the tandem process involving the formation of NH-1,2,3-triazoles and their reactions with electrophilic reactants in the synthesis of 1,4,5-substituted 1,2,3-triazoles.

How to Cite
Bakulev, V. A.; Beryozkina, T. A. Chem. Heterocycl. Compd. 2016, 52, 4. [Khim. Geterotsikl. Soedin. 2016, 52, 4.]

For this article in the English edition see DOI 10.1007/s10593-016-1821-y