SYNTHESIS OF HETEROCYCLIC SYSTEMS ON THE BASIS OF 4-BROMO-5-NITROPHTHALONITRILE
DOI:
https://doi.org/10.1007/315Keywords:
benzotriazole, bifunctional nucleophiles, 4-bromo-5-nitrophthalonitrile, dioxin, nucleophilic substitution, oxazine, Smiles rearrangementAbstract
Reaction of 4-bromo-5-nitrophthalonitrile with aromatic and heterocyclic N- and O-nucleophiles in the presence of bases leads to the sequential substitution of the bromine atom and the nitro group to give the corresponding heterocyclic systems previously undescribed in the literature.
Authors: I. G. Abramov, A. V. Smirnov, M. B. Abramova, S. A. Ivanovsky, and V. V. Plakhtinsky.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (9), pp 1062-1065