HETEROCYCLIC ANALOGS OF 5,12-NAPHTACENEQUINONE. 13. SYNTHESIS OF 4,11-DIAMINOANTHRA[2,3-<i>b</i>]FURAN-5,10-DIONES AND SULFUR-CONTAINING ANALOGS

Authors

  • Alexander S. Tikhomirov G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021 D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow 125047
  • Eugeny E. Bykov G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021
  • Yury N. Luzikov G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021
  • Alexander M. Korolev G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021
  • Andrey E. Shchekotikhin G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021 D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow 125047

DOI:

https://doi.org/10.1007/3305

Keywords:

amino derivatives, hetarene-fused anthracene-9, 10-diones, DFT calculations, oxidative dealkylation

Abstract

We have developed an effective method for the synthesis of 4,11-diaminoanthra[2,3-b]furan-5,10-dione and 4,11-diaminoanthra[2,3-b]thiophene-5,10-dione derivatives based on the substitution of 4,11-alkoxy groups with n-butylamine and subsequent oxidative dealkylation of n-butylamino groups via treatment with tetrabutylammonium hydroxide in DMSO.

 

 

Author Biography

Andrey E. Shchekotikhin, G. F. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya St., Moscow 119021 D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow 125047

профессор, заведующий кафедрой органической химии

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Published

2016-11-04

Issue

Vol. 52 No. 10 (2016)

Section

Original Papers