SYNTHESIS OF HIGHLY SUBSTITUTED 2-PYRIDONES

Authors

  • Maria A. Vodolazhenko SSI ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., 61001 Kharkiv
  • Nikolay Yu. Gorobets SSI ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., 61001 Kharkiv

DOI:

https://doi.org/10.1007/3387

Keywords:

2-pyridone, microwave-assisted synthesis, Hantzsch reaction, N, N'-dimethylformamide dimethyl acetal

Abstract

Modern methods for the synthesis of highly substituted 2-pyridones are overviewed making a special emphasis on the interaction between C1-electrophiles, α-carbonyl CH-acids, and active methylene nitriles under microwave irradiation.

Author Biographies

Maria A. Vodolazhenko, SSI ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., 61001 Kharkiv

Department of Chemistry of Heterocyclic Compounds, Leading Engineer

Nikolay Yu. Gorobets, SSI ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., 61001 Kharkiv

Department of Chemistry of Heterocyclic Compounds, Senior Researcher

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Published

2016-11-30

Issue

Vol. 52 No. 11 (2016): Non-classical methods of activation in chemistry of heterocyclic compounds

Section

Heterocycles in Focus