INTERACTION OF CONDENSED TETRAHYDROPYRIDO- [4,3-<i>d</i>]PYRIMIDIN-4-ONES WITH DEHYDROBENZENE – SYNTHESIS OF 6-VINYLPYRIMIDINONES FUSED WITH FIVE-MEMBERED HETEROCYCLE CONTAINING TWO OR THREE HETEROATOMS

Authors

  • Леонид Г. Воскресенский Peoples Friendship University of Russia
  • Наталья И. Гуранова Peoples Friendship University of Russia
  • Татьяна Н. Борисова Peoples Friendship University of Russia
  • Елена А. Сорокина Peoples Friendship University of Russia
  • Алексей В. Варламов Peoples Friendship University of Russia
  • Александр В. Аксенов Северо-Кавказский федеральный университет, ул. Пушкина, 1, Ставрополь 355009, Россия

DOI:

https://doi.org/10.1007/4203

Keywords:

arynes, azole ring, dehydrobenzene, pyridopyrimidinones, vinyl-substituted pyrimidinones, annulation, Hofmann cleavage.

Abstract

The reaction between dehydrobenzene and tetrahydropyrido[4,3-d]pyrimidin-4-ones condensed with isoxazole, thiazole, thiadiazole, or triazole rings resulted in Hofmann cleavage of the tetrahydropyridine moiety with the formation of 6-vinyl-substituted pyrimidones fused with the corresponding azole rings.

Author Biography

Леонид Г. Воскресенский, Peoples Friendship University of Russia

Organic Chemistry Department, professor

Downloads

Published

2018-03-23

Issue

Vol. 54 No. 2 (2018)

Section

Original Papers