SYNTHESIS AND FUNGICIDAL ACTIVITY OF MONOCYCLIC AND FUSED 1,2,3-TRIAZOLIUM-5-OLATES

Authors

  • Инна С. Хажиева Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Павел М. Демкин Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Олег С. Ельцов Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Юлия И. Нейн Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Татьяна А. Калинина Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Жи-Джин Фан State Key Laboratory of Organoelement Chemistry, Nankai University; National Collaborative Innovation Center of Chemical Science and Engineering, Nankai University
  • Лай Чен State Key Laboratory of Organoelement Chemistry, Nankai University
  • Бин Жао State Key Laboratory of Organoelement Chemistry, Nankai University
  • Татьяна В. Глухарева Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Юрий Ю. Моржерин Ural Federal University named after the first President of Russia B. N. Yeltsin

DOI:

https://doi.org/10.1007/4732

Keywords:

enamines, pyridinium, 1, 2, 3-triazoles, 3-triazolium-5-olates, crotonic condensation, antifungal properties, fungicidal activity, phytopathogenic fungi

Abstract

4-Acetyl-3-(2-aryl-2-oxoethyl)-1-phenyl-1Н-1,2,3-triazol-3-ium-5-olates, as well as 4-hydroxy-, 4-acetoxy-, and 4-amino derivatives of 2,6-diaryl-2H-[1,2,3]triazolо[1,5-а]pyridin-8-ium-3-olates were synthesized and tested for fungicidal activity against 9 strains of phytopathogenic fungi. Some compounds were identified that significantly inhibited the growth of one or several fungal strains. It was found that 4-acetyl-3-[2-(4-chlorophenyl)-2-oxoethyl]-1-phenyl-1Н-1,2,3-triazol-3-ium-5-olate had the best antifungal properties with the median effective concentration in the range of 2.28–47.75 µg/ml.

Authors: Inna S. Khazhieva, Pavel M. Demkin, Oleg S. Eltsov, Yulia I. Nein, Tatiana A. Kalinina, Zhi-Jin Fan, Lai Chen, Bin Zhao,
Tatiana V. Glukhareva, Yuri Yu. Morzherin

 

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Published

2018-11-12

Issue

Vol. 54 No. 10 (2018)

Section

Original Papers