REACTION OF ETHYL 3,3-DIAMINOACRYLATE WITH PYRIMIDINE SERIES <i>o</i>-CHLORO KETONES. SYNTHESIS OF PYRIDO[4,3-<i>d</i>]PYRIMIDINES AND 6<i>H</i>-1,3,6,7-TETRAAZAPHENALENES

Abstract

Cyclocondensation of ethyl 3,3-diaminoacrylate with 5-acetyl-4-chloropyrimidines gave ortho- and peri-condensed heterocycles formed through substitution of the chlorine atom by the α-carbon atom of the enediamine and condensation of the amino group with the carbonyl or by addition of the amino group to the pyridine ring.

Authors: O. Yu. Bakulina, E. M. Igumnova, D. V. Dar'in, and P. S. Lobanov

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (3), pp 466-471

http://link.springer.com/article/10.1007/s10593-013-1269-2