SYNTHESIS OF β-(<i>o</i>-HYDROXYBENZYL)PYRIDINES BY THREE-COMPONENT CONDENSATION OF AMMONIA, CARBONYL-SUBSTITUTED 4<i>Н</i>-CHROMENES, AND СН ACIDS

Authors

  • Дмитрий В. Осипов Самарский государственный технический университет
  • Виталий А. Осянин Samara State Technical University
  • Юрий Н. Климочкин

DOI:

https://doi.org/10.1007/4766

Keywords:

3-acyl-4Н-chromenes, 1, 3-dicarbonyl compounds, 7, 8-dihydroquinolin-5(6Н)-ones, enaminones, Michael reaction, multicomponent reactions.

Abstract

A series of pyridine derivatives containing a 2-hydroxybenzyl or (2-hydroxynaphthalen-1-yl)methyl substituent were obtained by treating
carbonyl-substituted 4Н-chromenes and 1Н-benzo[f]chromenes with ammonia and 1,3-dicarbonyl compounds or aromatic ketones as a result of the carbo-Michael reaction, chromane ring opening, and cyclodehydration.

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Published

2019-01-09

Issue

Vol. 54 No. 12 (2018)

Section

Original Papers