NOVEL DOMINO REACTION OF <i>N</i>-(CYANOMETHYL)-5,10-DIHYDRO[1]BENZOSILANO[3,2-<i>c</i>]PYRIDINIUM SALTS WITH SALICYLALDEHYDES

Abstract

The synthesis of benzosilanochromenoimidazopyridines was accomplished by a domino reaction of 5,5‑dimethyl-10-oxo- and 10-hydroxy-10-allyldihydrobenzosilanopyridinium N-cyanomethyl salts with salicyl- and 5-bromosalicylaldehydes. It was found that in the case of the 10-allyl-10-hydroxydihydrobenzosilanopyridinium salts the reaction occurred at both α-positions of the pyridine fragment to form a mixture of the isomeric benzosilano[3,2-c]- and benzosilano[2,3-d]chromenoimidazopyridines.

Authors: L. G. Voskressensky, E. A. Sokolova, A. A. Festa, V. N. Khrustalev, Nguyen Van Tuyen, Le Tuan Anh, and A. V. Varlamov

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (3), pp 484-490

http://link.springer.com/article/10.1007/s10593-013-1272-7